Evidence supporting the use of: Marking Nut Tree
For the health condition: Dermatitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The Marking Nut Tree (Semecarpus anacardium) has a long history of use in traditional Indian medicine, particularly Ayurveda and Siddha, for the treatment of various skin conditions, including dermatitis. Traditionally, the nut and its oil have been applied externally to treat eczema, ringworm, and other forms of dermatitis due to their reputed antimicrobial and anti-inflammatory properties. Classical texts such as the Sushruta Samhita reference its use for skin disorders. However, the use of Marking Nut is associated with significant caution, as the raw nut contains potent irritant compounds like bhilawanol and semecarpol, which can themselves cause severe contact dermatitis and blistering if not properly processed. Scientific studies on the efficacy and safety of Marking Nut Tree extracts for dermatitis are limited and mainly preclinical. Some in vitro and animal studies suggest anti-inflammatory and antimicrobial activities, but these findings do not directly confirm clinical benefits for dermatitis or guarantee safety in human topical applications. No robust, peer-reviewed clinical trials have established its efficacy or safety for this condition. Therefore, while traditional use is well documented, scientific evidence remains insufficient, and the risk of skin irritation or allergic reaction is significant. Caution is advised before considering its use for dermatitis.

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