Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Glycyrrhiza, commonly known as licorice, has a long history of use in traditional medicine for various skin conditions, including dermatitis. Historical records from Traditional Chinese Medicine and other herbal traditions cite licorice root as an ingredient in topical and systemic remedies aimed at relieving inflammation, itching, and irritation associated with dermatitis and eczema. The traditional rationale is based on its anti-inflammatory and soothing properties, attributed primarily to the compound glycyrrhizin.

However, while there are some preliminary scientific studies indicating that topical formulations containing licorice extract may reduce redness, swelling, and itching in eczema and other forms of dermatitis, the body of evidence remains limited and is mostly at the laboratory or small clinical trial stage. Systematic reviews generally conclude that more high-quality, large-scale clinical studies are needed to confirm efficacy and safety. Nevertheless, the traditional use is robust and well-documented across multiple cultures, which is why the evidence rating is moderate rather than low.

In summary, the use of Glycyrrhiza for dermatitis is primarily justified by traditional use, with modest supportive evidence from early scientific research but insufficient validation for routine clinical recommendation.

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