Chamomile (Matricaria chamomilla) is used both traditionally and with some scientific support to help manage dermatitis, particularly atopic dermatitis and mild eczema. Its traditional use as a topical anti-inflammatory and soothing agent is well-documented in European and Middle Eastern herbal medicine. Over the past few decades, scientific studies have investigated its efficacy in dermatological conditions due to its known constituents like chamazulene, bisabolol, and flavonoids, which exhibit anti-inflammatory, antioxidant, and mild antimicrobial properties.

Clinical evidence includes small randomized controlled trials and comparative studies. For example, a double-blind study (Aertgeerts et al., 1985) found that a chamomile cream was as effective as a low-potency hydrocortisone (0.25%) in reducing symptoms of eczema. Another trial (Patzelt-Wenczler & Ponce-Pöschl, 2000) demonstrated chamomile extract cream's non-inferiority to hydrocortisone in treating mild atopic eczema. However, most studies are limited by small sample sizes, short durations, and methodological variability.

Overall, the evidence suggests chamomile may be beneficial and safe for mild dermatitis when applied topically, but it is not as well-validated as standard corticosteroid treatments. Larger, well-designed studies are needed to confirm its efficacy and optimal usage.