Evidence supporting the use of: Sweet Orange
For the health condition: Depression

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Sweet Orange (Citrus sinensis) essential oil has a history of use in aromatherapy for mood enhancement, particularly for alleviating symptoms of depression. Scientific evidence supporting its use is modest but present. Several small-scale human and animal studies have examined the effects of sweet orange oil on mood and anxiety. For example, a 2012 study published in "Progress in Neuro-Psychopharmacology & Biological Psychiatry" found that inhalation of sweet orange essential oil reduced anxiety and improved mood in healthy volunteers exposed to anxiety-inducing situations. Other studies have reported similar effects, suggesting that olfactory stimulation with orange oil may modulate autonomic nervous system activity and influence neurotransmitter levels associated with mood regulation.

However, most of the available research is preliminary, with limitations such as small sample sizes, short intervention periods, and lack of blinding. The mechanisms by which orange oil exerts these effects are not fully understood but may involve the limbic system and serotonergic pathways. While there is a tradition of its use in aromatherapy for emotional well-being, the scientific evidence is not robust enough to recommend sweet orange oil as a standalone treatment for depression. It may, however, serve as a complementary approach for mood support in conjunction with established treatments. More rigorous clinical trials are needed to confirm its efficacy and safety for this indication.

More about Sweet Orange
More about Depression

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alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
ashwagandha
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basil
bergamot
beta caryophyllene
Bifidobacterium longum
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caffeine
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chamomile
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choline
citicoline
clove
coenzyme Q10 (CoQ10)
cordyceps
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turmeric
curcumin
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flavonols
folate
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ginseng
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hemp oil
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inositol
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l-tyrosine
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lavender
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liquid liver fractions
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maca
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omega-3 fatty acids
phenolic compounds
phosphatidylserine
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phytocannabinoids
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prebiotic blend (proprietary)
pregnenolone
protein
butyric acid
quercetin
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dopamine
egg
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eicosapentaenoic acid
estrogen
folinic acid
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fish
fatty acids
fungus
frankincense
guanidinoacetic acid
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Products containing Sweet Orange

We currently have no products on Caring Sunshine that contain this ingredient.