Synopsis

Source of validity: Scientific
Rating (out of 5): 2

There is emerging scientific evidence suggesting that prebiotic blends may have a role in supporting mood and alleviating symptoms of depression, although the evidence is still preliminary and not yet robust. Prebiotics are non-digestible food components (such as inulin, fructooligosaccharides, or galactooligosaccharides) that selectively stimulate the growth of beneficial gut bacteria. The gut-brain axis, the bidirectional communication pathway between the gastrointestinal tract and the central nervous system, has been implicated in mental health conditions, including depression. Several small-scale clinical trials and animal studies have shown that supplementation with certain prebiotics can modulate the gut microbiota, reduce inflammation, and influence the production of neurotransmitters involved in mood regulation (such as serotonin).

For example, a 2017 double-blind, placebo-controlled study published in Psychopharmacology found that healthy volunteers taking a prebiotic (B-GOS) for three weeks showed lower waking cortisol levels and improved emotional processing, both of which are relevant to depression. Another study in 2019 (Frontiers in Psychiatry) found that prebiotics, when combined with probiotics, improved depressive symptoms in individuals with major depressive disorder. However, these studies generally involve small sample sizes and short durations, and proprietary blends may differ in composition and efficacy. More large-scale, long-term studies are needed to conclusively establish the benefit of prebiotic blends for depression.

More about prebiotic blend (proprietary)
More about Depression

Other ingredients used for Depression

Other health conditions supported by prebiotic blend (proprietary)

Products containing prebiotic blend (proprietary)