Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Oxindole alkaloids are most notably found in the plant Uncaria tomentosa (cat’s claw), which has a long history of traditional use in South American herbal medicine, particularly for inflammatory conditions and immune support. There is some traditional precedent for the use of plants containing oxindole alkaloids for general well-being, which may incidentally include mood support. However, the direct use of oxindole alkaloids or Uncaria tomentosa specifically to treat or support depression is not a prominent or well-documented part of traditional medicine systems. The available evidence mostly comes from anecdotal or folk usage, rather than established traditional protocols targeting mood disorders.

On the scientific front, there is very limited research. A few preclinical studies have explored the neuroprotective and anti-inflammatory effects of oxindole alkaloids, but direct research on their impact on depression or depressive symptoms in humans is lacking. No clinical trials have robustly evaluated oxindole alkaloids for depression. Therefore, while there may be some traditional use that could be tangentially interpreted as mood support, there is neither strong traditional nor scientific evidence to justify their use specifically for depression.

More about Oxindole alkaloids
More about Depression

Other ingredients used for Depression

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Acetyl L-carnitine
algal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
ashwagandha
Waterhyssop
basil
bergamot
beta caryophyllene
Bifidobacterium longum
black tea
Indian frankincense
bасора
caffeine
Cannabis sativa oil
chamomile
Chinese salvia root
choline
citicoline
clove
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
turmeric
curcumin
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flavonols
folate
gardenia
ginger
ginkgo biloba
ginseng
gotu kola
Greek mountain tea
green tea
hemp oil
Indian tinospora
inositol
jujube
krill oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-carnosine
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lactium casein decapeptide
lavender
lion's mane
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liquid liver fractions
luteolin
maca
magnesium
magnolia
Marine lipid
Matcha
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Moringa
Muira puama
N-acetyl-cysteine (NAC)
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omega-3 fatty acids
phenolic compounds
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phytocannabinoids
polygala root
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prebiotic blend (proprietary)
pregnenolone
protein
butyric acid
quercetin
reishi mushroom
resveratrol
Rhodiola
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rosemary
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SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
sceletium
selenium
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velvet bean
vitamin B
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suma
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Beef liver
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estrogen
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Ginsenosides
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Gypenoside
Glutamate
Glycine
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Honokiol
Hypericin
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Hypericum
hyperforin
Helicteres isora
hericium mushroom
hemp
isoliquiritigenin
long pepper
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Indian fagonia
inositol phosphate
jasmine
Jatamansi
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lemon balm
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ligustilides
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magnolol
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Oroxylum indicum
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Oxindole alkaloids
Osthole
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pyrroloquinoline quinone
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Other health conditions supported by Oxindole alkaloids

Anxiety
Depression
Fatigue
Inflammation
Pain (general remedies for)
Stress

Products containing Oxindole alkaloids

We currently have no products on Caring Sunshine that contain this ingredient.