Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Morinda, especially Morinda citrifolia (commonly known as noni), has a long history of use in traditional medicine systems across Polynesia, Southeast Asia, and parts of India. In these traditions, noni fruit and juice have been employed to address a variety of ailments, including mood disorders and symptoms suggestive of depression. The rationale for its use in depression is largely anecdotal, with traditional healers reporting its benefits for enhancing mood and overall well-being.

Scientific research on Morinda’s efficacy specifically for depression is limited. A few preclinical studies have investigated the effects of noni extracts on animal models of depression, suggesting possible antidepressant-like activity, potentially via modulation of neurotransmitter systems such as serotonin or dopamine. However, these studies are preliminary and have not been robustly replicated or translated into high-quality human clinical trials. Most available research focuses on other purported benefits of Morinda, such as its antioxidant or immune-modulating properties, rather than its effects on depressive symptoms.

In summary, the use of Morinda for depression is primarily justified by traditional practices, with only minimal and preliminary scientific evidence available. Thus, the evidence supporting its use for this specific condition is rated as low (1/5).

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