Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Caffeine is a central nervous system stimulant most commonly found in coffee, tea, and various energy drinks. Its use in supporting or addressing depression is primarily based on scientific observations, though the evidence is moderate and not definitive. Several epidemiological studies have noted an association between moderate caffeine consumption (particularly from coffee) and a reduced risk of depression. For example, a large-scale study published in the journal JAMA Internal Medicine (2011) found that women who drank more coffee had a lower risk of developing depression. The proposed mechanisms include caffeine’s ability to increase the availability of neurotransmitters like dopamine and serotonin, which are implicated in mood regulation, as well as its mild psychostimulant effects that can counteract some symptoms of depression such as fatigue and low motivation. However, clinical use of caffeine as a treatment for depression is not standard practice, and excessive intake may worsen anxiety, insomnia, and even depressive symptoms in some individuals, especially those sensitive to stimulants. Systematic reviews and meta-analyses suggest that while caffeine may have some protective effect against the development of depression, it is not a substitute for established antidepressant therapies. In summary, there is scientific evidence supporting a mild benefit from caffeine in lowering depression risk, but the evidence is not strong enough to recommend caffeine as a mainstay treatment for depression.

More about caffeine
More about Depression

Other ingredients used for Depression

Other health conditions supported by caffeine

Products containing caffeine