Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Butea monosperma, also known as Flame of the Forest or Palash, has a long history of use in traditional Ayurvedic medicine. While it is primarily valued for its anti-inflammatory, antimicrobial, and antiparasitic properties, some traditional texts and practices also describe its use as a nervine tonic that may support mental health and alleviate symptoms of stress or mild depression. However, there is very limited direct scientific research specifically examining the antidepressant effects of Butea monosperma. A few preclinical studies (mostly in animal models) have suggested possible central nervous system activity, but robust clinical trials in humans are lacking. The majority of references to its use for depression come from ethnobotanical surveys and Ayurvedic literature, where it is sometimes used in combination with other herbs for mood disorders. In summary, while Butea monosperma has traditional support for its use in mood-related conditions, the scientific evidence is weak and largely preclinical. Further research, particularly well-designed human trials, would be needed to validate its efficacy and safety for depression.

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