Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Ardisia is a genus of plants used in traditional medicine in parts of Asia, particularly in Chinese and Southeast Asian herbal practices. Some species, such as Ardisia crenata and Ardisia japonica, are included in traditional remedies thought to improve mental well-being or calm the spirit. However, these uses are primarily based on historical or ethnomedicinal knowledge rather than robust scientific evidence. There are very limited preclinical studies investigating the neuropharmacological effects of Ardisia species, and almost no clinical trials evaluating their efficacy for depression. The use of Ardisia in the context of depression is typically justified by its inclusion in multi-herb formulas, rather than direct evidence of effectiveness against depressive symptoms. As such, while Ardisia may appear in traditional practices aimed at mood or mental health, current evidence supporting its use for depression is weak and largely anecdotal. No major pharmacological studies or systematic reviews support its use as an antidepressant, and any benefits reported are not substantiated by modern clinical science.

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