Spirulina, a blue-green algae, has been traditionally consumed as a food source in certain cultures but has gained popularity worldwide as a dietary supplement for its purported health benefits, including its use in supporting or treating debility (general weakness or lack of energy). The justification for spirulina’s use in debility is primarily supported by limited scientific evidence rather than strong traditional roots for this specific application.

Several small clinical studies and animal experiments have investigated spirulina’s effects on fatigue, immunity, and general well-being. Spirulina is rich in protein, vitamins (such as B12), minerals (notably iron), and antioxidants, which may contribute to its potential to help in cases of nutritional deficiency-related debility. For example, a few trials have reported improvements in energy levels, reduction in fatigue, and increased exercise performance among elderly individuals or those with chronic fatigue when supplemented with spirulina. Additionally, some studies suggest spirulina may enhance immune function and help correct anemia, which can contribute to feelings of weakness.

However, the clinical evidence is limited in size and quality, with many studies being small, not placebo-controlled, or lacking rigorous methodology. The aggregate evidence suggests possible benefits for mild cases of debility, particularly when related to nutritional deficits, but does not strongly support its use as a standalone treatment for more severe or medically complex causes of weakness. More robust and larger-scale clinical trials are needed to fully validate spirulina’s efficacy for this purpose.