Evidence supporting the use of: Protein (unspecified)
For the health condition: Debility

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Protein supplementation is scientifically validated as a supportive treatment for debility, especially in cases of malnutrition, chronic illness, aging, or recovery from surgery or trauma. Debility often involves muscle wasting, generalized weakness, and impaired immune function, all of which can be exacerbated by inadequate protein intake. Numerous clinical studies have demonstrated that protein supplementation can help preserve or restore lean body mass, improve muscle strength, and enhance physical function in debilitated individuals. For instance, older adults experiencing sarcopenia (age-related muscle loss) or patients recovering from illness or surgery benefit from increased dietary protein to stimulate muscle protein synthesis and reduce catabolism. Medical nutrition guidelines, such as those from the European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN), recommend protein supplementation as a cornerstone of nutritional therapy for patients with debility or at risk of malnutrition. While the specific type and amount of protein may vary, the overall consensus is that adequate protein intake is crucial for recovery and functional improvement in debility. The evidence base is robust, supported by randomized controlled trials and systematic reviews, though optimal dosing and long-term outcomes continue to be areas of research.

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