Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phyllanthus species, particularly Phyllanthus amarus and Phyllanthus niruri, have a longstanding history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine. In these traditions, Phyllanthus is commonly indicated for conditions described as "general debility," fatigue, or weakness, often linked to its perceived tonic, rejuvenating, and adaptogenic properties. The plant is typically used in formulations intended to restore vitality, improve digestion, and address liver-related issues, which are sometimes believed to contribute to overall debility.

However, scientific studies specifically evaluating Phyllanthus for the treatment of general debility in humans are lacking. Most modern research has focused on its hepatoprotective, antiviral (especially against hepatitis B), and antioxidant actions, rather than on energy enhancement or anti-fatigue effects. While some animal studies suggest possible adaptogenic or anti-stress effects, these findings have not been robustly replicated or translated into clinical trials addressing debility as a primary outcome. Therefore, the use of Phyllanthus for debility remains primarily supported by traditional knowledge rather than scientific evidence. The evidence rating reflects the strong traditional use but limited scientific validation for this specific indication.

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