Evidence supporting the use of: Gastrodia
For the health condition: Cramps and Spasms

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Gastrodia elata, known as Tian Ma in traditional Chinese medicine (TCM), has been used for centuries to address neurological symptoms such as cramps, spasms, dizziness, and convulsions. Its use is primarily rooted in TCM theory, where it is said to "extinguish wind" and "relieve spasms." Historical texts document its use for disorders described as "internal wind," which modern practitioners often interpret as involuntary muscular contractions, tremors, or spasms associated with conditions like epilepsy, stroke, or tetanus.

Phytochemical studies have identified several active constituents in Gastrodia, such as gastrodin and vanillin, which are believed to have neuroprotective and anticonvulsant properties based on in vitro and animal studies. Some preclinical research demonstrates that gastrodin can modulate neurotransmitter activity, reduce neuronal excitability, and protect against induced seizures and muscle spasms in rodent models. However, robust clinical trials in humans are scarce, and most evidence supporting its use for cramps and spasms is anecdotal or derived from traditional practice rather than modern clinical studies.

In summary, the use of Gastrodia to support or treat cramps and spasms is primarily justified by traditional use, with moderate preclinical scientific support but limited human clinical evidence. The overall quality and quantity of scientific validation remain insufficient for a higher evidence rating.

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