Evidence supporting the use of: Ferula assafoetida
For the health condition: Cramps and Spasms

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ferula assafoetida, commonly known as asafoetida, has a long history of use in traditional medicine systems such as Ayurveda and Unani for the management of cramps and spasms, particularly those related to the digestive tract (e.g., intestinal colic, flatulence, and abdominal pain). Traditional texts often describe its actions as carminative, antispasmodic, and digestive, recommending it for relieving abdominal discomfort and muscle spasms. While animal studies have suggested some antispasmodic effects—possibly due to its volatile oils and compounds like ferulic acid—there is limited high-quality clinical research in humans to substantiate these claims. The few in vitro and animal studies available indicate that asafoetida may relax smooth muscles by modulating calcium channels or exerting mild anti-inflammatory effects. However, robust clinical trials confirming efficacy in human cramping or spasmodic conditions are lacking. Thus, its use for cramps and spasms is primarily justified by traditional and historical practice, with only modest preclinical support and a lack of direct scientific validation in humans. Asafoetida continues to be used in some cultures for digestive complaints, but caution is advised due to insufficient modern evidence.

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