Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Pistacia integerrima, commonly known as "karkatshringi" or "gall of Pistacia integerrima," has been used in traditional Ayurvedic and Unani medicine to manage respiratory ailments, particularly coughs, including spastic (or dry, irritating) cough. Its usage is documented in classical Ayurvedic texts such as the Charaka Samhita and Bhavaprakasha, where it is described as having expectorant, anti-inflammatory, and bronchodilator properties. The galls are typically administered in powdered form or as part of polyherbal formulations intended to soothe the respiratory tract and reduce coughing.

Scientific studies on Pistacia integerrima are limited but do provide some support for its traditional use. Preliminary pharmacological investigations have reported that extracts from the galls exhibit antitussive (cough-suppressing), anti-inflammatory, and antimicrobial effects in animal models. For instance, studies have shown that the methanolic extract of the galls can significantly reduce cough frequency induced by irritants in experimental animals, suggesting a potential benefit in spastic cough. However, these studies are mostly preclinical, with a lack of robust human clinical trials to confirm efficacy and safety in treating coughs.

In summary, while the use of Pistacia integerrima gall for cough (spastic) is primarily justified by traditional medical systems and is somewhat supported by preliminary scientific research, high-quality clinical evidence is still lacking. Thus, the tradition-based justification is stronger than scientific validation at present.

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