Evidence supporting the use of: Ivy (unspecified)
For the health condition: Cough (spastic)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ivy (most commonly referring to Hedera helix, or English ivy) is used in modern phytotherapy for the treatment of cough, particularly spastic or productive cough, and respiratory tract conditions such as bronchitis. The use of ivy leaf extract is supported by both traditional European herbal medicine and an increasing body of scientific research. Ivy leaf contains saponins—particularly α-hederin and hederacoside C—that are believed to exert expectorant, bronchodilatory, and anti-inflammatory effects.

Clinical studies, including randomized controlled trials and observational studies, have demonstrated that standardized ivy leaf extracts can help reduce cough frequency and intensity, loosen bronchial secretions, and improve symptoms in patients with acute and chronic bronchitis, and other respiratory tract diseases. The European Medicines Agency (EMA) has recognized the traditional and well-established use of ivy leaf preparations for these purposes. However, while there is moderate-quality evidence for symptomatic relief, the studies frequently have limitations such as small sample sizes, short durations, or lack of placebo controls. Meta-analyses suggest a positive effect, but also highlight the need for larger, high-quality trials.

Overall, ivy leaf is scientifically validated for use as a supportive treatment for cough, including spastic cough, but the strength of evidence is moderate rather than robust. It is widely available in over-the-counter syrups and drops for cough relief, particularly in Europe.

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