Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Adenophora, particularly the root of Adenophora stricta or Adenophora triphylla, has a long-standing history of use in traditional East Asian medicine, especially in Chinese and Korean herbal practices, for the treatment of coughs, including spastic (irritative, persistent) coughs. The root, known as "Sha Shen" in Chinese medicine, is often employed in formulations aimed at moistening the lungs, relieving dryness, and treating chronic coughs with dry throat, sometimes associated with yin deficiency. Classical texts and modern materia medica reference its use in decoctions for conditions characterized by dry, irritating coughs. While there are some in vitro and animal studies suggesting potential anti-inflammatory and immunomodulatory properties of Adenophora extracts, robust clinical evidence in humans is lacking. Its traditional use for cough relief is primarily based on empirical knowledge passed down through generations and inclusion in authoritative herbal compendia. Modern pharmacological studies are limited and do not yet provide strong validation for its efficacy in treating spastic cough. Therefore, its use is best characterized as traditional, with a moderate level of supporting evidence based on its longstanding inclusion in herbal medicine rather than rigorous scientific validation.

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