Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Fritillary (most commonly referring to the bulbs of Fritillaria cirrhosa, Fritillaria thunbergii, or related species) has a long history of use in Traditional Chinese Medicine (TCM) as a remedy for cough and other respiratory symptoms. These bulbs, known as Chuan Bei Mu or Zhe Bei Mu, are commonly prescribed to "moisten the lungs," "clear heat," and "transform phlegm." Historical Chinese medical texts document their use for various types of cough, especially those associated with thick sputum or dryness.

Some modern pharmacological studies have identified alkaloids in Fritillary bulbs (such as peimine and peiminine) that may exhibit antitussive (cough-suppressing) and expectorant effects in animal models. However, robust clinical trial evidence in humans is limited. Most available studies are preclinical or observational, and systematic reviews often conclude that while there are promising traditional uses and preliminary data, high-quality clinical trials are lacking.

In summary, the use of Fritillary for cough is primarily justified by traditional use, with a modest but incomplete scientific basis. The evidence level is rated as 3, reflecting strong traditional support and a moderate amount of preclinical scientific research, but insufficient rigorous clinical data.

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