Evidence supporting the use of: Khella
For the health condition: Cough (dry)
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Khella (Ammi visnaga) has been traditionally used in some herbal medicine systems, particularly in the Middle East and Mediterranean regions, for respiratory conditions including coughs and asthma. The primary active constituents in Khella are khellin and visnagin, which are known for their smooth muscle relaxant effects, especially in the bronchi and urinary tract. Historical texts and traditional herbal practices have employed Khella as an antispasmodic and bronchodilator, which could theoretically provide relief in dry (non-productive) cough by relaxing bronchial muscles and reducing spasms that provoke coughing. However, most of the traditional use and limited scientific research has focused on its role in asthma, angina, and kidney stones rather than specifically on dry cough. There is a lack of robust clinical evidence or controlled studies directly assessing the efficacy of Khella for dry cough, and its use for this indication is mainly based on broader traditional respiratory applications. Because of this, the evidence supporting Khella for dry cough is weak, and it should not be considered a primary or well-validated treatment for that symptom. Caution is also advised due to reported side effects and potential toxicity of khellin at higher doses.
Other ingredients used for Cough (dry)
aloe veraalpha-pinene
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waterhyssop
benegut perilla (proprietary)
beta-pinene
black currant
black pepper
radish
Indian frankincense
cat's claw
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
garlic bulb
ginger
glehnia root
greek mountain tea
onion
green tea
heartwood
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jujube
lemon
licorice root
marshmallow
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ophiopogon root
oregano
parsley
pear
phellodendron amurense
platycodon root
plum fruit
polygala root
pomegranate
thyme
vitamin C
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
Indian bael
malabar nut
alpinia galangal
hedychium spicatum
inula racemosa
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pistacia integerrima gall
fumaria parviflora
fritillaria
yerba santa
elecampane
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menthol oil
Alcohol
Agastache
Anamarrhena
Ambergris
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Asarum heterotropoides
Aconite
Asafoetida
Aerva lanata
Asam gelugor
Adenophora
Allium tuberosum
Asarum sieboldii
Atractylone
Black Seed
Bermuda Grass
Bryonia
Bayleaf
Bael
Butternut
Baccharoides anthelmintica
black salt
Bee products
Buddha's Hand
banana
Bassia scoparia
Burning Bush
Balloon Flower
Belamcanda
Bergenia
Cactus
Citron
Citrus
Cineole
Capsaicin
Cistus
Cubeb
Cowslip
Chaenomeles lagenaria
Calamus
Cinnamaldehyde
Clerodendrum indicum
Dragonhead
Diterpenes
Dichrostachys glomerata
Echinacea
Elder
Ephedrine
Fruit
Fritillary
Fernbush
Flavoglycosides
Fringed Pink
Glehnia littoralis
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Gallesia
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Poppy