Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Andrographis paniculata, commonly known as "King of Bitters," is widely used in traditional herbal medicine systems, particularly in Ayurveda, Traditional Chinese Medicine, and Thai medicine, for the management of respiratory tract infections, including cough (dry). Historical records and ethnobotanical surveys document its use as an expectorant and for soothing coughs and sore throats. Traditionally, it is believed to possess anti-inflammatory, antipyretic, and immunostimulatory properties, which may help alleviate the symptoms of upper respiratory tract infections.

Modern research provides limited but promising evidence supporting these traditional uses. Several randomized controlled trials and meta-analyses have evaluated Andrographis extract (often standardized to andrographolide content) for acute respiratory tract infections. These studies suggest that Andrographis may reduce the severity and duration of cough and other symptoms such as sore throat and nasal congestion, especially when taken at the early onset of symptoms. However, most studies focus on mixed respiratory infections, not specifically on dry cough, and the methodological quality varies. The mechanism is thought to involve anti-inflammatory and immunomodulatory effects, but more rigorous, targeted clinical trials are needed to confirm efficacy specifically for dry cough.

In summary, the use of Andrographis paniculata for treating dry cough is primarily justified by a long history of traditional use, with moderate scientific evidence supporting its general use in upper respiratory tract infections.

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