Evidence supporting the use of: Rosavin
For the body system: Cortisol

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rosavin is one of the primary bioactive compounds found in Rhodiola rosea, an adaptogenic herb traditionally used in Russia and Scandinavia to combat fatigue and improve resilience to stress. Scientific studies suggest that Rhodiola rosea extracts, standardized for rosavin content, may modulate the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol production and stress responses. Several randomized controlled trials and animal studies have shown that Rhodiola supplementation can reduce stress-induced elevations in cortisol and support mental performance under stress.

However, while the overall evidence for Rhodiola rosea is moderate, studies specifically isolating rosavin are less common; most research uses whole extracts containing rosavin along with other compounds (such as salidroside). Meta-analyses and systematic reviews indicate that Rhodiola may have a modest effect on fatigue, stress, and cortisol regulation, but effects are typically small to moderate, and more high-quality research focusing on rosavin alone is needed. Thus, use of rosavin (as part of Rhodiola rosea extracts) to support the cortisol body system is supported by a moderate degree of scientific evidence, but definitive conclusions require further investigation.

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Products containing Rosavin

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