Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jatamansi (Nardostachys jatamansi) has a long history of use in traditional Ayurvedic and Unani medicine for its calming and adaptogenic properties. In these systems, it is often used to soothe the mind, reduce stress, and promote restful sleep—effects that are indirectly related to the modulation of cortisol, the body’s primary stress hormone. Ancient texts describe Jatamansi as a "medhya rasayana," meaning a rejuvenator of the mind and nerves, which has led to its use in conditions believed to be caused by stress or nervous imbalance.

However, while there is traditional justification for its use in what would now be considered stress-related conditions, direct scientific evidence linking Jatamansi to the modulation of cortisol levels is limited. A handful of preclinical studies suggest that extracts of Jatamansi may have anti-stress and anxiolytic effects in animal models, possibly through antioxidant and neuroprotective pathways. Yet, robust human clinical data are lacking, and studies explicitly measuring cortisol modulation in humans are scarce.

Therefore, the use of Jatamansi to support the cortisol body system is primarily justified by tradition, with a modest but not strong body of supportive evidence. Its inclusion for this purpose is common in traditional formulations, but further research would be needed to validate these claims scientifically.

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