Evidence supporting the use of: Genseng (not specified)
For the body system: Cortisol

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ginseng, particularly Panax ginseng and Panax quinquefolius (American ginseng), is widely used in traditional medicine for its adaptogenic properties—meaning it may help the body adapt to stress. Modern scientific research has explored these claims, focusing on ginseng's potential to modulate the hypothalamic-pituitary-adrenal (HPA) axis and its influence on cortisol, the primary stress hormone. Several animal and human studies suggest that ginsenosides, the active compounds in ginseng, may blunt excessive cortisol secretion in response to stress and help restore balance to the HPA axis. For example, a 2015 systematic review (Kennedy et al., 2015) found moderate evidence that ginseng supplements can reduce perceived stress and fatigue, and some small clinical trials report reductions in cortisol levels after ginseng supplementation. However, the evidence is not entirely consistent, with some trials showing minimal or no effect, and most studies are limited by small sample sizes and short durations. Overall, while there is a scientific rationale and some supporting data for ginseng's use in supporting healthy cortisol balance, the evidence base is still emerging and not yet robust. More large-scale, well-controlled trials are needed to confirm its effectiveness for this application.

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Products containing Genseng (not specified)

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