Evidence supporting the use of: Vitamin C (unspecified)
For the health condition: Convalescence

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C (ascorbic acid) has a scientifically supported role in convalescence, particularly due to its involvement in immune function and tissue repair. During periods of recovery from illness, injury, or surgery, the body's demand for Vitamin C increases as it is required for collagen synthesis, antioxidant defense, and the functioning of various immune cells. Clinical studies have shown that Vitamin C deficiency can impair wound healing and increase susceptibility to infections, both of which are relevant during convalescence. Supplementation has been demonstrated to reduce the duration and severity of certain conditions, such as the common cold, and may support faster recovery in hospitalized patients, especially those with low baseline levels or under high oxidative stress. However, while there is general consensus on the importance of adequate Vitamin C intake during recovery, robust evidence from randomized controlled trials specifically targeting convalescence populations is limited, and findings regarding supplemental Vitamin C in well-nourished individuals are mixed. Most guidelines recommend ensuring at least the recommended dietary allowance (RDA) is met during convalescence, with higher doses reserved for those with proven or suspected deficiency. Overall, the use of Vitamin C in convalescence is justified by its established biological roles and moderate clinical evidence, particularly in cases where deficiency or increased demand is likely.

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