Schisandra (Schisandra chinensis) has a long history of use in Traditional Chinese Medicine (TCM), where it is valued as an adaptogen and general tonic, particularly during periods of convalescence—recovery from illness or fatigue. In TCM, Schisandra is believed to "tonify the Qi," support the liver, and help restore vitality, which aligns with the goals of convalescence: rebuilding strength and resilience after illness. While there is a robust traditional foundation for its use, direct scientific evidence specifically supporting Schisandra for convalescence is limited. Most modern research has focused on its adaptogenic, hepatoprotective, and antioxidant properties, with studies indicating potential benefits in improving physical endurance, cognitive function, and liver health. However, these studies often involve healthy subjects or animal models rather than individuals in a state of convalescence. In summary, the use of Schisandra for convalescence is primarily justified by traditional practices, particularly in East Asian medicine. Scientific research offers indirect support due to its general restorative effects, but there is a lack of high-quality clinical trials directly investigating its efficacy specifically in convalescent patients.