Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Glucan peptides, particularly β-glucans derived from sources such as yeast, fungi, and cereals, have been studied for their immunomodulatory and supportive effects during periods of convalescence. Scientific evidence indicates that β-glucans can enhance innate and adaptive immune responses by activating macrophages, neutrophils, and natural killer cells, which are crucial in the recovery phase following illness or surgery. Additionally, some studies suggest that β-glucans may improve resistance to infections and support the healing process by modulating inflammatory responses and promoting tissue repair.

Clinical trials in humans are somewhat limited but show promising results. For example, a few randomized controlled trials have reported improved immune function and a reduction in the incidence of infections in patients receiving β-glucan supplementation during recovery from surgery or illness. These effects are thought to be related to the ability of β-glucans to prime the immune system and enhance the body's defense mechanisms during vulnerable periods.

While most of the available evidence focuses on β-glucans rather than specifically on "glucan peptides," the term is sometimes used interchangeably in the context of medical foods, especially in East Asia. Overall, the evidence base is moderate (rated 3/5) and supports the use of glucan peptides as an adjunct in convalescence, particularly for their immunomodulatory properties. However, more large-scale, high-quality clinical trials are needed to confirm these benefits and establish optimal dosing.

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