Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Immunoglobulins, commonly referred to as antibodies, are proteins produced by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The medical use of immunoglobulins, particularly intravenous immunoglobulin (IVIG) and specific immunoglobulin preparations, is well-established and scientifically validated for the treatment and prevention of various contagious diseases. Immunoglobulins can be derived from pooled plasma of healthy donors or from individuals with high levels of specific antibodies (hyperimmune globulins).

For certain contagious diseases—such as hepatitis B, rabies, tetanus, varicella-zoster, and measles—immunoglobulin preparations are used as post-exposure prophylaxis to provide immediate, passive immunity for individuals who are non-immune or at high risk. This approach is especially important when there is insufficient time for active vaccination to confer protection. In addition, IVIG is used to treat some severe infections and immune deficiencies where patients cannot produce adequate antibodies themselves.

The efficacy and safety of immunoglobulin therapy for these indications have been demonstrated in numerous clinical studies and are supported by guidelines from health authorities such as the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC). Thus, the use of immunoglobulins in the prevention and treatment of certain contagious diseases is based on robust scientific evidence.

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