Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Neem (Azadirachta indica) has been used in traditional medicine systems, particularly Ayurveda and Unani, for a variety of eye conditions, including conjunctivitis. Historical texts and folk practices describe the use of neem leaf extracts, decoctions, or water for washing inflamed eyes, with the belief that its antimicrobial and anti-inflammatory properties can help alleviate symptoms of eye infections. The rationale behind this use stems from neem's broad-spectrum antibacterial and antiviral activity, which has been demonstrated in laboratory studies, though these are mostly in vitro or animal-based and not specific to conjunctivitis in humans.

However, robust scientific clinical evidence supporting neem’s efficacy for conjunctivitis in humans is lacking. While laboratory studies have shown neem extracts can inhibit the growth of certain pathogens associated with eye infections, no high-quality randomized controlled trials have directly evaluated neem's effectiveness or safety for conjunctivitis treatment in clinical settings. Reports of its use are predominantly anecdotal or based on traditional knowledge, and no major ophthalmic guidelines recommend neem as a standard treatment. Therefore, while neem’s use for conjunctivitis is rooted in tradition and supported by some plausible mechanisms, scientific validation remains limited, and caution is advised due to potential for irritation or allergic reactions when used in or around the eyes.

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