Evidence supporting the use of: Thiamine (Vitamin B1)
For the health condition: Congestive Heart Failure

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Thiamine (Vitamin B1) has a modest but scientifically supported role in the management of congestive heart failure (CHF), especially in specific contexts. Thiamine deficiency is relatively common in patients with CHF, particularly those on chronic diuretic therapy (such as loop diuretics), which can increase urinary thiamine excretion. Thiamine is essential for myocardial energy metabolism, and deficiency can impair cardiac function. Several small clinical studies and case reports have shown that thiamine supplementation can lead to improvements in left ventricular ejection fraction and symptoms in CHF patients with thiamine deficiency. However, large-scale, high-quality randomized controlled trials are lacking, and the benefit appears most significant in those with documented or suspected deficiency rather than in all patients with CHF. Guidelines from major cardiology societies do not recommend routine thiamine supplementation for all CHF patients, but recognize its use in those with deficiency. Overall, while there is a plausible biological rationale and limited clinical evidence supporting thiamine supplementation in thiamine-deficient CHF patients, the general use for all CHF patients is not strongly supported. The evidence is rated as low to moderate in quality and strength.

More about Thiamine (Vitamin B1)
More about Congestive Heart Failure

Products containing Thiamine (Vitamin B1)

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