Evidence supporting the use of: Thiamin
For the health condition: Congestive Heart Failure

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Thiamin (vitamin B1) has a scientific basis for use in supporting patients with congestive heart failure (CHF), though the overall quality and quantity of evidence are limited. Several studies have demonstrated that patients with CHF, especially those treated with long-term loop diuretics like furosemide, are at increased risk of thiamin deficiency due to increased urinary excretion. Thiamin is an essential cofactor in myocardial energy metabolism, and deficiency can impair cardiac function. Small randomized controlled trials and observational studies have suggested that thiamin supplementation may improve left ventricular ejection fraction and symptoms in some CHF patients with documented deficiency. However, these studies are generally small, short-term, and sometimes methodologically limited. Meta-analyses and systematic reviews acknowledge the potential benefit but also stress the need for larger, high-quality clinical trials to establish definitive efficacy and safety. Current heart failure guidelines do not universally recommend thiamin supplementation except in cases of identified deficiency or risk factors for deficiency. In summary, there is scientific rationale and some supporting evidence for thiamin supplementation in CHF, particularly for patients at risk of deficiency, but routine use is not broadly endorsed due to limited robust clinical data.

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Products containing Thiamin

We currently have no products on Caring Sunshine that contain this ingredient.