Evidence supporting the use of: Thiamin
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Thiamin (vitamin B1) has a scientific basis for use in supporting patients with congestive heart failure (CHF), though the overall quality and quantity of evidence are limited. Several studies have demonstrated that patients with CHF, especially those treated with long-term loop diuretics like furosemide, are at increased risk of thiamin deficiency due to increased urinary excretion. Thiamin is an essential cofactor in myocardial energy metabolism, and deficiency can impair cardiac function. Small randomized controlled trials and observational studies have suggested that thiamin supplementation may improve left ventricular ejection fraction and symptoms in some CHF patients with documented deficiency. However, these studies are generally small, short-term, and sometimes methodologically limited. Meta-analyses and systematic reviews acknowledge the potential benefit but also stress the need for larger, high-quality clinical trials to establish definitive efficacy and safety. Current heart failure guidelines do not universally recommend thiamin supplementation except in cases of identified deficiency or risk factors for deficiency. In summary, there is scientific rationale and some supporting evidence for thiamin supplementation in CHF, particularly for patients at risk of deficiency, but routine use is not broadly endorsed due to limited robust clinical data.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
arjun tree
astragalus
black garlic
coenzyme Q10 (CoQ10)
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
garlic bulb
ginseng
hawthorn
l-arginine
l-carnitine
l-citrulline
l-taurine
marine lipid
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
ophiopogon root
potassium
resveratrol
thiamin (vitamin B1)
ubiquinol
vitamin D
zinc
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Arjuna
Allicin
Arginine orotate
Astragaloside
Arjunic Acid
Black Seed
Chinese Silkvine
Catecholamine
Cowherb
Docosahexaenoic Acid
Danshen
Digitalis
Eicosapentaenoic Acid
Foxglove
Fatty acids
Flavanols
Glycoside
Theophylline
Other health conditions supported by Thiamin
AlcoholismCardiovascular Disease
Congestive Heart Failure
Diabetes
Fatigue
Memory and Brain Function
Mental Illness
Nerve Damage
Nervous Exhaustion
Peripheral Neuropathy