Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Frangula (commonly known as Buckthorn, particularly Frangula alnus, also called Alder Buckthorn) has been traditionally used as a laxative to treat constipation, including atonic (lazy) colon. Historical use dates back to traditional European herbal medicine, where the bark was valued for its purgative effects. The activity is attributed to the presence of anthraquinone glycosides, compounds that stimulate peristalsis in the colon and promote bowel movements. These constituents are similar to those found in other well-known stimulant laxatives such as senna and cascara.

There is some pharmacological rationale behind its use: anthraquinones increase intestinal motility and alter water and electrolyte secretion, which can be particularly helpful in cases of atonic colon, where the bowel muscles lack proper tone. However, while traditional use is well-documented and there is some overlap with scientifically accepted mechanisms of action for stimulant laxatives, rigorous clinical trials specifically for Frangula in atonic colon are limited or lacking. The evidence remains mostly anecdotal or based on historical texts and general pharmacology of anthraquinone-containing plants.

Therefore, while Frangula is commonly used in traditional herbal medicine for constipation and atonic colon, the scientific evidence from controlled human studies supporting this use is not robust. Caution is advised due to potential side effects and the risk of dependency with long-term use.

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