Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Digestion resistant maltodextrin (DRM), also known as resistant maltodextrin, is a type of soluble dietary fiber that resists digestion in the small intestine and reaches the colon, where it is fermented by gut microbiota. Scientific studies support its use in promoting colon health, particularly in conditions involving reduced colonic motility, such as atonic colon. The primary mechanism is through the prebiotic effects of DRM: it stimulates the growth of beneficial bacteria like bifidobacteria and lactobacilli, which produce short-chain fatty acids (SCFAs) as metabolic byproducts. SCFAs, especially butyrate, are known to enhance colonic motility, improve mucosal integrity, and may contribute to increased stool bulk and frequency.

Several randomized controlled trials and reviews (e.g., EFSA Journal 2011; Lamsal, 2009, Cereal Foods World) have shown that DRM increases stool frequency and softens stool consistency in healthy and constipated individuals. These effects are particularly relevant in the context of atonic colon, where reduced motility leads to constipation. However, while the evidence indicates benefits for general colonic function and constipation, direct studies specifically addressing "atonic colon" are limited, and most research focuses on functional constipation or general digestive health. Thus, the evidence is moderate (rated 3) and primarily supports symptomatic improvement rather than addressing underlying pathophysiology of atonic colon.

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