Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Propionibacterium freudenreichii subsp. shermanii is a probiotic bacterium traditionally used in cheese production, especially Swiss-type cheeses. Recent scientific research has explored its potential health benefits, including its role in gut health and as an adjunct in managing inflammatory bowel diseases such as colitis. Preclinical studies, primarily in animal models, have shown that P. freudenreichii can reduce the severity of colitis symptoms. These effects are thought to be mediated via the production of short-chain fatty acids (notably propionate), immunomodulatory effects, and anti-inflammatory metabolites.

For example, a 2015 study (Cousin et al., Frontiers in Microbiology) demonstrated that administration of P. freudenreichii reduced inflammation and improved histological scores in a mouse model of chemically induced colitis. The proposed mechanisms included modulation of cytokine production and strengthening of the intestinal barrier. However, clinical evidence in humans is limited to a few small pilot studies and in vitro data, with no robust randomized controlled trials directly supporting its use in treating colitis in humans as of mid-2024.

In summary, while there is promising preclinical evidence and plausible mechanisms, the overall scientific validation is still at an early stage, and more human trials are needed to confirm efficacy and safety. Thus, the evidence rating is 2 out of 5, indicating preliminary but insufficient scientific support for the use of P. freudenreichii shermanii in colitis.

More about Propionibacterium freudenreichii shermanii
More about Colitis

Other ingredients used for Colitis

Akkermansia muciniphila
algal oil
Aloe vera
anthocyanins
apple
astaxanthin
bacillus clausii
bacillus coagulans
bacillus subtilis
barberry
beta caryophyllene
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bilberry
bio ecolian (proprietary)
blueberry
bromelain
butyrate triglyceride
cat's claw
Chinese salvia root
chlorella
Coptis chinensis
cowage seed
turmeric
curcumin
fiber blend (proprietary)
flavonols
garlic bulb
ginger
green tea
hemp oil
immunoglobin G
inulin
isomalto-oligosaccharide
L-glutamine
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus lactis
Lactobacillus paracasei
lactiplantibacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lactococcus lactis
Lactoferrin
licorice root
N-acetyl-cysteine (NAC)
plantain
pomegranate
prebiotic blend (proprietary)
butyric acid
quercetin
resveratrol
Saccharomyces boulardii
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Triphala
Zinc
xanthium (cockleburs)
blackboard tree
picrorhiza kurroa
Swertia
buckthorn
anemarrhena asphodeloides
Algae
apple cider vinegar
apigenin
anamu
Alchornea
andrographolide
Asteraceae
Acemannan
Amor seco
astragalin
Bifidobacterium
Bifidobacterium adolescentis
Boswellic Acid
bael
Basidiomycota
Boswellia
Baccharoides anthelmintica
Bifidobacterium animalis
black nightshade
bacteria
Bifidobacteria
Bacillus
cactus
Curcuminoid
curcumen
Curcuma
cabbage
Clostridium butyricum
colocynth
diterpenes
Euphorbia
fucoidan
fiber
Frangula
gallic acid
Glycomacropeptides
Guava
Glycyrrhetinic acid
Hedyotis
Helicteres isora
Humic acid
hericium mushroom
Immunoglobulin G
Kefir
Lactobacillus plantarum
Lactobacillus pentosus
Lactobacillus sakei
Lactobacillus kefiri
Lactococcus rhamnosus
Lactococcus casei
Lactobacillus delbrueckii
Lactobacillus johnsonii
Lactobacillus
L. lactis
Mucilage
Nimbidin
Oligosaccharides
Oxymatrine
Osthole
polysaccharides
Plantago
phlorotannins
Propionibacterium freudenreichii
probiotics
Pediococcus acidilactici
Patrinia
Peptides
rosmarinic acid
Rhus coriaria
Slippery Elm
Scabrous Gentian
Triterpenes
Tayuya
Trametes
Varuna

Other health conditions supported by Propionibacterium freudenreichii shermanii

Colitis
Inflammatory Bowel Disorders
Irritable Bowel Syndrome

Products containing Propionibacterium freudenreichii shermanii

We currently have no products on Caring Sunshine that contain this ingredient.