Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glutamine is an amino acid that serves as a fuel source for enterocytes (intestinal cells) and plays a role in maintaining gut barrier function and modulating inflammation. Its use in colitis, particularly inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease, is supported by some preclinical and clinical research, though evidence is not robust or universally conclusive. Animal studies frequently show that glutamine supplementation can reduce intestinal inflammation, enhance mucosal healing, and improve gut integrity. In humans, results are mixed: several small clinical trials and pilot studies have investigated oral or enteral glutamine supplementation in patients with colitis or IBD, with some reporting improvements in mucosal repair and symptoms, while others found no significant benefit compared to placebo. Systematic reviews suggest that while glutamine appears safe and may have potential as an adjunctive therapy, larger and more rigorous randomized controlled trials are needed to establish efficacy. Most clinical guidelines do not currently recommend glutamine as a standard treatment for colitis due to insufficient evidence. Thus, while there is a plausible scientific rationale and some preliminary validation, the clinical evidence supporting its use remains limited.

More about l-glutamine
More about Colitis

Other ingredients used for Colitis

Other health conditions supported by l-glutamine

Products containing l-glutamine

Nature's Sunshine AIVIA Hydrate
Nature's Sunshine Focus Attention
Nature's Sunshine Gaba Plus
Nature's Sunshine l-Glutamine
Nature's Sunshine Solstic Cardio
Nature's Sunshine Target TS-II Formula
Nature's Sunshine Ultrabiome DTX
Nature's Sunshine VitaWave