Evidence supporting the use of: Blueberry
For the health condition: Colitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Blueberry (Vaccinium spp.) has garnered scientific interest for its potential role in supporting colitis, particularly due to its high content of polyphenols, especially anthocyanins. Several preclinical studies have demonstrated that blueberry supplementation can ameliorate symptoms of colitis in animal models. For example, research published in PLoS One (2017) and Journal of Nutritional Biochemistry (2015) found that blueberry extracts reduced inflammation, oxidative stress, and histological damage in chemically-induced colitis in mice. The mechanisms are believed to involve modulation of inflammatory cytokines (such as TNF-α, IL-6), enhancement of antioxidant enzyme activity, and beneficial shifts in gut microbiota composition.

Human evidence is more limited, but a small pilot study (Nutrition Research, 2019) indicated that a blueberry-enriched diet was well tolerated in patients with mild ulcerative colitis and suggested potential benefits on inflammation markers and gut microbiome diversity. However, data from large-scale, randomized controlled trials are lacking, and thus, the evidence is not robust enough for clinical recommendations. The use of blueberry for colitis is not rooted in traditional medicine, but in emerging nutritional and biomedical research.

In summary, while promising preclinical data exist and preliminary human studies are encouraging, more rigorous clinical trials are needed. The current level of scientific support for blueberry in colitis can be rated as moderate (3 out of 5), indicating some evidence but insufficient for definitive clinical endorsement.

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algal oil
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anamu
andrographolide
anemarrhena asphodeloides
anthocyanins
apigenin
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astaxanthin
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bacillus subtilis
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bilberry
bio ecolian (proprietary)
black nightshade
blackboard tree
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Boswellia
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bromelain
buckthorn
butyrate triglyceride
butyric acid
cabbage
cactus
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chlorella
Clostridium butyricum
colocynth
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diterpenes
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flavonols
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gallic acid
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ginger
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green tea
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hemp oil
hericium mushroom
Humic acid
immunoglobin G
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inulin
isomalto-oligosaccharide
Kefir
L-glutamine
L. lactis
lactiplantibacillus plantarum
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Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
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Lactobacillus kefiri
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