Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium longum is a probiotic bacterium that has been studied for its potential role in supporting or treating colitis, particularly ulcerative colitis and other forms of inflammatory bowel disease (IBD). Several clinical and preclinical studies provide moderate scientific evidence for its efficacy.

Research indicates that B. longum can modulate the gut microbiota, enhance intestinal barrier function, and reduce inflammation. For example, randomized controlled trials using Bifidobacterium longum in combination with other probiotics (such as in the formulation VSL#3) have shown benefits in reducing disease activity and maintaining remission in ulcerative colitis patients (Gionchetti et al., 2004). Animal studies also demonstrate that B. longum can decrease colonic inflammation and improve mucosal health.

However, most clinical studies use B. longum as part of a multi-strain probiotic, making it difficult to attribute effects to this species alone. Standalone trials of B. longum are fewer, but some show reduced inflammation markers and symptom improvement in colitis models. The safety profile is favorable, and the mechanism involves modulation of immune responses and competition with pathogenic bacteria.

In summary, there is scientific support—though not yet at the highest level of evidence—for using Bifidobacterium longum as an adjunct in managing colitis, especially when combined with other probiotics. More large-scale, strain-specific trials are needed for definitive conclusions.

More about Bifidobacterium longum
More about Colitis

Other ingredients used for Colitis

Other health conditions supported by Bifidobacterium longum

Products containing Bifidobacterium longum

Nature's Sunshine Bifidophilus Flora Force
Nature's Sunshine Eleven Elevated (NutriBiome)
Nature's Sunshine Probiotic Eleven
Nature's Sunshine Sunshine Heroes Probiotic Power