Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Aloe vera has historically been used for a variety of gastrointestinal ailments, including colitis, largely due to its traditional reputation as a soothing and anti-inflammatory agent. Recent scientific research has explored its efficacy in inflammatory bowel diseases, including ulcerative colitis. Aloe vera gel contains compounds such as polysaccharides (notably acemannan), vitamins, minerals, and antioxidants that are thought to exert anti-inflammatory and immune-modulating effects. Several small clinical trials and animal studies have investigated its effects in colitis. A randomized, double-blind, placebo-controlled study published in Alimentary Pharmacology & Therapeutics (2004) found that oral aloe vera gel was more effective than placebo in reducing disease activity in patients with mild to moderate ulcerative colitis, although the sample size was small. Other preclinical studies in animal models have shown that aloe vera can reduce colonic inflammation and oxidative stress. However, the overall quality of evidence is limited by small sample sizes, short study durations, and some inconsistent results. Major clinical guidelines do not currently recommend aloe vera as a standard therapy for colitis due to insufficient evidence. In summary, while there is some promising scientific data suggesting potential benefit, the evidence is not strong or extensive enough to support widespread use, and more rigorous large-scale studies are needed to confirm its efficacy and safety in colitis.

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Other ingredients used for Colitis

Other health conditions supported by Aloe vera

Products containing Aloe vera

Nature's Sunshine CleanStart Mild
Nature's Sunshine Aloe Vera (Freeze Dried)
Nature's Sunshine Aloe Vera Gel
Nature's Sunshine Aloe Vera Juice
Nature's Sunshine Aloe Vera Juice (Whole Leaf)
Nature's Sunshine Liquid Cleanse