Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Chenopodium, particularly species such as Chenopodium ambrosioides (commonly known as epazote or wormseed), has a longstanding history of use in traditional medicine systems, especially in Central and South America. Historically, indigenous and folk practitioners have employed Chenopodium preparations for a variety of gastrointestinal complaints, including colic in children, intestinal worms, and dyspepsia. The rationale for its use in colic is generally linked to its reputed carminative (gas-relieving) and antispasmodic properties, as well as its ability to expel intestinal parasites, which were sometimes presumed to cause colic-like symptoms in children.

However, scientific validation for the efficacy and safety of Chenopodium in treating colic, particularly in children, is weak. There are very few, if any, well-designed clinical studies evaluating its effectiveness for this purpose. Moreover, concerns about the toxicity of Chenopodium essential oil (which contains ascaridole, a potentially harmful compound) have led to caution in its medicinal use, especially in pediatric populations. Most modern medical sources do not recommend its use for colic due to safety risks and lack of proven benefit. Therefore, while its use is supported by tradition, evidence quality is poor and safety is a significant concern.

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