Evidence supporting the use of: Sambucus Nigra (unspecified)
For the health condition: Colds (decongestant)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Sambucus nigra, commonly known as elderberry, has a longstanding history of traditional use for treating colds and flu-like symptoms, particularly in Europe. However, scientific research in recent decades has begun to investigate its efficacy more rigorously. Several randomized, placebo-controlled clinical trials have examined elderberry extract's effects on upper respiratory symptoms. Notably, a 2004 study published in the journal Journal of International Medical Research found that elderberry extract reduced the duration and severity of influenza symptoms compared to placebo. Another 2016 meta-analysis suggested elderberry supplementation might reduce the duration and severity of cold symptoms in air travelers.
The proposed mechanism is that elderberry's bioactive compounds, especially flavonoids like anthocyanins, may block viral entry into cells and modulate inflammatory cytokines, which could account for symptomatic relief. However, study sample sizes have been relatively small, and not all trials are of high methodological quality. While results are promising, further large-scale, high-quality studies are needed to confirm efficacy and clarify optimal dosing and formulation. In summary, the use of Sambucus nigra as a decongestant and for cold symptom relief is supported by both tradition and some scientific evidence, though the strength of evidence is moderate rather than definitive.
More about Sambucus Nigra (unspecified)
More about Colds (decongestant)
Other ingredients used for Colds (decongestant)
allspicewaterhyssop
basil
beta-pinene
black cumin
black currant
black pepper
radish
capsaicinoids
chen pi
citrus oil
clove
turmeric
echinacea purpurea
elderberry
forsythia
garlic bulb
ginger
greek mountain tea
green tea
horseradish
honeysuckle
lemon
licorice root
mint
mustard seed
oregano
peppermint oil
pineapple
pomegranate
quercetin
rhizome
rosemary
schizonepeta
spearmint leaf
thyme
vitamin C
wasabia japonica
water
zinc
hyssop
cardamom
atractylodes
capsicum
mugwort
alpinia galangal
ferula assafoetida
boxthorne
lemongrass
yerba santa
chrysanthemum
sweet flag
eucalyptus
menthol oil
abies spectabilis
horehound
Sichuan pepper
indigo leaves
cayenne pepper
Alcohol
Agastache
Alpha-terpineol
Asarum heterotropoides
Andrographis
Asteracea
allyl isothiocyanate
Allium tuberosum
Arani
Atractylone
Baphicacanthus cusia
Balsam
Bishop's Weed
Black galingale
Bitter Grass
berry
Bee products
Buddha's Hand
Borneol
Coconut
Clerodendrum trichotomum
Capillary Artemisia
Citron
Citrus
Cineole
Capsaicin
Cajuput
Cinnamaldehyde
Costus
Dragonhead
Echinacea
Elder
Mustard
salt
Sandalwood
Sweet Orange alcohol
Other health conditions supported by Sambucus Nigra (unspecified)
ArthritisColds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Fever
Infection (viral)
Influenza
Sinus Infection
Sore Throat
Urinary Tract Infections