Evidence supporting the use of: Indigo leaves
For the health condition: Colds (decongestant)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Indigo leaves (from Indigofera tinctoria or related species) have been used in traditional medicine systems, particularly in South Asia and parts of Africa, for various ailments, including as a remedy for colds and respiratory congestion. In Ayurveda and some forms of traditional Chinese medicine, preparations made from indigo leaves have been employed as decongestants or to alleviate symptoms such as cough, sore throat, and nasal congestion. The traditional rationale is often based on the plant's purported anti-inflammatory, antimicrobial, or expectorant properties.

However, scientific validation for these uses is limited. While some laboratory studies have identified antimicrobial and anti-inflammatory compounds in indigo leaves, there is little direct clinical evidence to support their efficacy specifically as a decongestant or cold remedy in humans. Most of the available information comes from ethnobotanical surveys and anecdotal reports rather than controlled trials. As such, the use of indigo leaves for colds is primarily justified by tradition, and the overall quality of evidence is low (rated 2 out of 5), acknowledging longstanding cultural use and some plausible biological activities but lacking robust scientific confirmation.

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