Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Glycyrrhiza, commonly known as licorice root, has a long history of traditional use in various cultures, particularly in traditional Chinese medicine (TCM) and Ayurveda, for the treatment of respiratory ailments, including colds and coughs. It has been used as a demulcent (soothing agent for mucous membranes) and expectorant, and is believed by traditional practitioners to help relieve congestion and soothe irritated throats. The key active compound, glycyrrhizin, is thought to possess anti-inflammatory and mild antiviral properties, which might contribute to symptom relief during upper respiratory tract infections. However, while there is some preliminary scientific research suggesting licorice root extracts can modulate immune responses and inhibit certain viruses in vitro, robust clinical evidence supporting its use specifically as a decongestant for colds in humans is limited. Most of the available evidence is either anecdotal or derived from traditional use, rather than from controlled clinical trials. Safety concerns such as hypertension and hypokalemia with prolonged or high-dose use also temper enthusiasm for its therapeutic application. In summary, licorice root's use as a decongestant for colds is primarily justified by traditional practices, with limited direct scientific validation.

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