Evidence supporting the use of: Rhemannia
For the health condition: Cold Hands and Feet

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rehmannia (Rehmannia glutinosa) is a staple herb in Traditional Chinese Medicine (TCM), where it is often used in formulas aimed at nourishing the blood and tonifying the yin. Cold hands and feet are commonly interpreted in TCM as signs of “yang deficiency” or “blood deficiency,” conditions for which Rehmannia is a frequent ingredient in herbal blends such as Si Wu Tang or Shou Wu Wan. In this context, Rehmannia is believed to “warm” and “nourish” the body by supporting blood production and circulation, indirectly addressing cold extremities.

However, there is limited scientific research directly linking Rehmannia or its active constituents to improvements in peripheral circulation or the specific symptom of cold hands and feet. Most clinical and preclinical studies focus on other effects, such as its potential for blood glucose regulation, neuroprotection, or anti-inflammatory properties. The use of Rehmannia for cold hands and feet thus remains primarily supported by traditional usage rather than modern scientific validation. The evidence rating is 2, reflecting a robust traditional basis but a lack of direct scientific studies confirming efficacy for this particular symptom.

More about Rhemannia
More about Cold Hands and Feet

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