Evidence supporting the use of: Triterpenes
For the health condition: Cirrhosis of the Liver

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Triterpenes are a large class of naturally occurring compounds found in many medicinal plants, including those used in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda. In these systems, triterpene-rich herbs (such as Ganoderma lucidum (Reishi), Glycyrrhiza glabra (licorice), and others) have been used for centuries to support liver health and treat liver diseases, including cirrhosis. The traditional rationale is based on empirical observations of improvement in symptoms associated with chronic liver conditions, such as jaundice and fatigue, rather than direct understanding of the pathology of cirrhosis itself.

Some preclinical (animal and in vitro) studies have shown that certain triterpenes possess hepatoprotective, anti-inflammatory, and anti-fibrotic effects, suggesting a mechanistic basis for liver protection. However, robust clinical evidence in humans specifically supporting the use of isolated triterpenes or triterpene-rich plant extracts for the treatment of cirrhosis is lacking. Most of the scientific literature consists of preliminary studies, and few high-quality randomized controlled trials exist.

Overall, the use of triterpenes to support or treat cirrhosis is primarily rooted in traditional practices, with limited scientific validation. While some early data are promising, the current level of evidence does not strongly support routine use in clinical practice for cirrhosis, and further research is needed to establish safety and efficacy.

More about Triterpenes
More about Cirrhosis of the Liver

Products containing Triterpenes

We currently have no products on Caring Sunshine that contain this ingredient.