Evidence supporting the use of: Catechin
For the health condition: Cirrhosis of the Liver

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Catechin, a type of flavonoid found in green tea and other plants, has been studied for its potential hepatoprotective (liver-protecting) effects, including in the context of liver cirrhosis. Most of the scientific evidence for catechin’s use in cirrhosis comes from animal models and limited human clinical trials. Experimental studies have shown that catechins may reduce oxidative stress and inflammation in the liver, mechanisms that are implicated in the development and progression of cirrhosis. For example, in vitro and animal studies demonstrate that green tea catechins can attenuate liver fibrosis, inhibit the activation of hepatic stellate cells (key players in fibrosis), and decrease lipid peroxidation.

Some small-scale human trials and case reports have suggested benefits of catechin or green tea extracts in improving liver function tests in patients with chronic liver diseases, including cirrhosis. However, the evidence is not robust, and large, well-controlled clinical trials are lacking. Further, some concerns have been raised about potential hepatotoxicity of high-dose green tea extracts in susceptible individuals. Thus, while there is a scientific rationale and preliminary evidence for catechin's use in liver cirrhosis, the evidence is still limited (rated 2 out of 5), and it cannot be widely recommended as a treatment without further research.

More about Catechin
More about Cirrhosis of the Liver

Products containing Catechin

We currently have no products on Caring Sunshine that contain this ingredient.