Evidence supporting the use of: Thiamin (vitamin B1)
For the body system: Circulatory System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Thiamin (vitamin B1) is scientifically validated as essential for proper cardiovascular function. Its primary role in the circulatory system is related to its involvement in energy metabolism and nerve function, both of which are critical for the heart and blood vessels. Thiamin acts as a coenzyme in the metabolism of carbohydrates, enabling the conversion of food into energy, which is necessary for the contraction and function of cardiac muscle. Deficiency in thiamin can lead to beriberi, a disease that manifests in two forms—wet and dry. The "wet" form directly affects the cardiovascular system, causing symptoms such as tachycardia (rapid heartbeat), enlarged heart, edema (fluid accumulation), and ultimately heart failure if untreated.

Numerous studies and clinical observations have documented the link between thiamin deficiency and cardiovascular complications. For example, thiamin deficiency is frequently observed in patients with congestive heart failure, especially those taking diuretics, which can increase urinary loss of thiamin. Supplementation in such cases has shown improvements in heart function and symptoms. However, while deficiency correction is clearly beneficial, the evidence for thiamin supplementation in individuals with normal thiamin status for further enhancing circulatory health is limited. In summary, thiamin’s critical role in energy metabolism and its necessity for heart function are well-established, justifying its use in supporting the circulatory system when deficiency is present.

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