Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B3, also known as niacin, has some scientific evidence supporting its role in promoting circulation, including to the brain. Niacin is a vasodilator, meaning it widens blood vessels, which can enhance blood flow. This effect is well-documented and underlies its use in treating hyperlipidemia, as increased blood flow can help reduce cardiovascular risk. In the context of brain circulation, some studies have indicated that niacin supplementation can improve cerebral blood flow, potentially offering benefits in conditions where blood supply to the brain is compromised, such as in cerebrovascular disease or after a stroke. However, the evidence in humans is limited and mostly comes from small-scale studies or animal models. Clinical trials investigating niacin's effect on cognition or neuroprotection have shown mixed results, with some suggesting modest benefits in improving cognitive function or recovery after brain ischemia, while others have found no significant effect. Traditional use of niacin to improve "poor circulation" is also common, but the scientific rationale is primarily based on its pharmacological effects as a vasodilator. Overall, while there is a scientific basis for niacin's role in supporting circulation to the brain, the strength of clinical evidence is moderate, warranting a rating of 3 out of 5.

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