Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Centella triterpenes, the active compounds in Centella asiatica (commonly known as gotu kola), are used to support poor circulation, particularly in conditions such as chronic venous insufficiency (CVI). There is moderate scientific evidence supporting this use. Several clinical studies and reviews have indicated that extracts rich in triterpenes (such as asiaticoside, madecassoside, and asiatic acid) may improve microcirculation, increase venous tone, and reduce symptoms like swelling, heaviness, and pain in patients with CVI and related circulatory disorders. For example, a 2013 review in "Phytomedicine" and clinical trials published in journals such as "Angiology" and "International Journal of Angiology" report improvements in capillary filtration rate, edema, and subjective symptom scores after treatment with standardized Centella triterpene extracts. The proposed mechanisms include strengthening of connective tissue around blood vessels and reduction of capillary permeability.

However, while there is a body of clinical and experimental evidence, most studies are relatively small and of varying quality, often using standardized extracts (e.g., TECA, TTFCA) in specific dosages. Larger, high-quality randomized controlled trials are still needed to fully confirm efficacy and safety. Thus, the use of Centella triterpenes for poor circulation is scientifically supported but not conclusively proven at the highest level of evidence.

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