Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Capsaicinoids, the active compounds in chili peppers (Capsicum species), have been investigated for their effects on circulation due to their role in inducing vasodilation and enhancing blood flow. Scientific studies indicate that capsaicinoids activate transient receptor potential vanilloid 1 (TRPV1) receptors, leading to the release of vasodilatory neuropeptides such as substance P and calcitonin gene-related peptide (CGRP). This mechanism can result in localized increases in blood flow and warmth when applied topically, which has led to the development of capsaicin creams for symptomatic relief in certain circulatory issues like peripheral neuropathy.

Some small human and animal studies have suggested that capsaicin intake or topical application may improve peripheral circulation, reduce blood pressure, and enhance endothelial function. However, the evidence is limited by small sample sizes, short durations, and variability in dosages and formulations. There is also some epidemiological evidence linking dietary chili pepper consumption to improved cardiovascular health outcomes, but causality is unclear.

While traditional medicine systems have used chili peppers to "stimulate circulation," modern scientific validation remains modest. The overall evidence supporting capsaicinoids for treating poor circulation is thus rated as moderate to low (2 out of 5), with most benefits observed in topical rather than systemic applications. More robust clinical trials are needed to confirm efficacy and safety for this specific indication.

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