Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Capsaicinoids, the active compounds found in chili peppers (notably capsaicin), have been investigated for their effects on cardiovascular health and circulation. Several scientific studies suggest that capsaicinoids may help improve peripheral circulation through vasodilation, primarily by activating the transient receptor potential vanilloid 1 (TRPV1) receptors on vascular smooth muscle. This activation can lead to the release of vasodilatory neuropeptides such as calcitonin gene-related peptide (CGRP), promoting increased blood flow in certain vascular beds.

Animal studies and limited human trials have demonstrated that capsaicin can cause local and systemic vasodilation, and may transiently increase blood flow. For example, topical capsaicin has been shown to improve microcirculation in the skin. Dietary consumption of capsaicin has also been linked to modest improvements in endothelial function and reductions in blood pressure in some small-scale studies. However, the evidence is not robust, with most studies being small, short-term, or not directly targeting populations with poor circulation.

In summary, while there is a plausible scientific mechanism and some preliminary evidence suggesting capsaicinoids may support circulation, the overall quality and quantity of clinical research are limited. Thus, the use of capsaicinoids for poor circulation is supported by modest scientific evidence, but larger and more rigorous human studies are needed to establish efficacy and safety for this specific indication.

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